Database of Structural Repeats in Proteins



Protein prenyltransferase alpha subunit - PFTA


Protein prenylation is the posttranslational attachment of either a farnesyl group or a geranylgeranyl group via a thioether linkage (-C-S-C-) to a cysteine at or near the carboxyl terminus of the protein. Farnesyl and geranylgeranyl groups are polyisoprenes, unsaturated hydrocarbons with a multiple of five carbons; the chain is 15 carbons long in the farnesyl moiety and 20 carbons long in the geranylgeranyl moiety. The alpha subunit is thought to participate in a stable complex with the isoprenyl substrate. In the alpha subunits of both types of protein prenyltransferases, seven tetratricopeptide repeats are formed by pairs of helices that are stabilised by conserved intercalating residues.

Link to other db

InterPro:

IPR002088

PROSITE:

PS51147

Pfam:

PF01239

Number of PDB chains with PFTA repeat: 192
1 - 50

PDB

Chain

UniProt

Name

Organism

Repeat annotation

Copies

Score
5G04
X
Q9UJX3
Anaphase-promoting complex subunit 7
Homo sapiens (Human)
135-163, 164-198, 199-228, 232-266, 287-320, 404-437, 438-471, 492-522
8
0.76
5G05
X
Q9UJX3
Anaphase-promoting complex subunit 7
Homo sapiens (Human)
73-110, 135-163, 164-198, 199-228, 232-267, 492-524
6
0.83
5G05
C
Q9UJX2
Cell division cycle protein 23 homolog
Homo sapiens (Human)
70-96, 150-184, 222-257, 262-296, 297-326
5
0.79
4UI9
P
Q9UJX2
Cell division cycle protein 23 homolog
Homo sapiens (Human)
78-111, 170-202, 222-257, 262-296, 297-326
5
0.82
5A31
P
Q9UJX2
Cell division cycle protein 23 homolog
Homo sapiens (Human)
78-111, 170-202, 222-257, 262-296, 297-326
5
0.82
5G04
C
Q9UJX2
Cell division cycle protein 23 homolog
Homo sapiens (Human)
78-111, 150-184, 222-257, 258-292, 293-326, 413-439
6
0.82
5G05
P
Q9UJX2
Cell division cycle protein 23 homolog
Homo sapiens (Human)
170-202, 227-261, 262-296, 297-326
4
0.85
2OOE
A
Q99LI7
Cleavage stimulation factor subunit 3
Mus musculus (Mouse)
20-44, 45-78, 79-110, 116-152, 369-403
5
0.76
5VHH
U
Q99460
26S proteasome non-ATPase regulatory subunit 1
Homo sapiens (Human)
41-73, 388-415, 526-558, 562-592, 597-626
5
0.65
4DZW
A
Q95WL3
Trypanosoma cruzi
258-286, 287-315, 317-360
3
0.71
4DXJ
A
Q95WL3
Trypanosoma cruzi
257-286, 287-315, 317-362
3
0.76
1YHM
B
Q8WS26
Trypanosoma cruzi
259-285, 286-315, 317-362
3
0.69
3ID0
A
Q8WS25
Trypanosoma cruzi
259-285, 286-315, 317-362
3
0.71
3DYF
A
Q86C09
Trypanosoma brucei
263-290, 291-320, 322-367
3
0.73
3DYG
A
Q86C09
Trypanosoma brucei
263-290, 291-320, 322-367
3
0.72
5AFX
B
Q86C09
Trypanosoma brucei
264-289, 291-320, 322-367
3
0.67
3DYH
B
Q86C09
Trypanosoma brucei
264-289, 291-320, 322-367
3
0.71
3EGT
B
Q86C09
Trypanosoma brucei
263-291, 292-320, 322-367
3
0.72
5AEL
B
Q86C09
Trypanosoma brucei
264-289, 290-320, 322-367
3
0.72
3EFQ
B
Q86C09
Trypanosoma brucei
264-289, 291-320, 322-367
3
0.71
3DYH
A
Q86C09
Trypanosoma brucei
264-289, 291-320, 322-367
3
0.71
2OGD
B
Q86C09
Trypanosoma brucei
264-289, 291-320, 322-367
3
0.70
5AHU
D
Q86C09
Trypanosoma brucei
264-291, 292-320, 322-361
3
0.73
2P1C
B
Q86C09
Trypanosoma brucei
264-289, 291-320, 322-367
3
0.71
3EFQ
A
Q86C09
Trypanosoma brucei
263-290, 291-320, 322-367
3
0.73
3EGT
A
Q86C09
Trypanosoma brucei
263-290, 291-320, 322-367
3
0.73
3DYF
B
Q86C09
Trypanosoma brucei
262-291, 292-320, 322-367
3
0.74
5AHU
B
Q86C09
Trypanosoma brucei
264-291, 292-320, 322-361
3
0.72
4RXE
B
Q86C09
Trypanosoma brucei
264-289, 292-320, 322-367
3
0.64
2OGD
A
Q86C09
Trypanosoma brucei
264-289, 291-320, 322-367
3
0.71
3S4W
B
Q80V62
Fanconi anemia group D2 protein homolog
Mus musculus (Mouse)
187-216, 221-249, 254-290, 502-545, 1000-1035, 1093-1122
6
0.73
6BCO
D
Q7TN37
Transient receptor potential cation channel subfamily M member 4
Mus musculus (Mouse)
247-273, 386-417, 422-448, 458-484
4
0.64
6BCO
B
Q7TN37
Transient receptor potential cation channel subfamily M member 4
Mus musculus (Mouse)
247-273, 386-417, 422-448, 458-484
4
0.64
6BCO
A
Q7TN37
Transient receptor potential cation channel subfamily M member 4
Mus musculus (Mouse)
247-273, 386-417, 422-448, 458-484
4
0.64
6BCO
C
Q7TN37
Transient receptor potential cation channel subfamily M member 4
Mus musculus (Mouse)
247-273, 386-417, 422-448, 458-484
4
0.64
2PF4
A
Q76MZ3
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
Mus musculus (Mouse)
16-43, 317-351, 358-388, 394-429
4
0.72
3SE6
A
Q6P179
Endoplasmic reticulum aminopeptidase 2
Homo sapiens (Human)
801-830, 834-866, 867-902
3
0.76
5AB0
C
Q6P179
Endoplasmic reticulum aminopeptidase 2
Homo sapiens (Human)
677-712, 801-833, 834-867, 868-908
4
0.83
5AB2
A
Q6P179
Endoplasmic reticulum aminopeptidase 2
Homo sapiens (Human)
638-675, 801-830, 834-867, 868-907
4
0.82
5AB2
B
Q6P179
Endoplasmic reticulum aminopeptidase 2
Homo sapiens (Human)
801-830, 834-867, 868-908
3
0.80
5AB0
A
Q6P179
Endoplasmic reticulum aminopeptidase 2
Homo sapiens (Human)
801-830, 834-867, 879-907
3
0.80
5K1V
B
Q6P179
Endoplasmic reticulum aminopeptidase 2
Homo sapiens (Human)
638-675, 801-830, 834-867, 868-903
4
0.78
5CU5
A
Q6P179
Endoplasmic reticulum aminopeptidase 2
Homo sapiens (Human)
801-830, 834-867, 868-907
3
0.82
5J6S
B
Q6P179
Endoplasmic reticulum aminopeptidase 2
Homo sapiens (Human)
764-786, 801-830, 834-867, 868-900
4
0.69
5CU5
B
Q6P179
Endoplasmic reticulum aminopeptidase 2
Homo sapiens (Human)
801-830, 834-867, 868-907
3
0.82
5K1V
A
Q6P179
Endoplasmic reticulum aminopeptidase 2
Homo sapiens (Human)
638-675, 801-833, 834-867, 868-907
4
0.86
4JBS
B
Q6P179
Endoplasmic reticulum aminopeptidase 2
Homo sapiens (Human)
801-833, 834-865, 866-907
3
0.87
4EBA
B
Q6CII8
mRNA 3'-end-processing protein RNA14
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1
101-136, 142-178, 185-223, 303-336, 502-536
5
0.75
3Q75
A
Q55S71
Cryptococcus neoformans var
25-54, 55-89, 90-123, 166-198, 207-243
5
0.80
3Q78
A
Q55S71
Cryptococcus neoformans var
25-54, 55-89, 91-125, 166-198, 208-243
5
0.79