Database of Structural Repeats in Proteins

Armadillo repeat - ARM


The armadillo repeat is an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila melanogaster segment polarity gene armadillo involved in signal transduction through wingless. Animal Arm-repeat proteins function in various processes, including intracellular signalling and cytoskeletal regulation, and include such proteins as beta-catenin, the junctional plaque protein plakoglobin, the adenomatous polyposis coli (APC) tumour suppressor protein, and the nuclear transport factor importin-alpha, amongst others. A subset of these proteins is conserved across eukaryotic kingdoms. In higher plants, some Arm-repeat proteins function in intracellular signalling like their mammalian counterparts, while others have novel functions. The 3-dimensional fold of an armadillo repeat is known from the crystal structure of beta-catenin, where the 12 repeats form a superhelix of alpha helices with three helices per unit.

Link to other db

InterPro:

IPR000225

PROSITE:

PS50176

SMART:

SM00185

Pfam:

PF00514

Number of PDB chains with ARM repeat: 450


1 - 50

PDB

Chain

UniProt

Name

Organism

Repeat annotation

Copies

Score

3UKY
B
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
71-109, 112-151, 152-193, 243-282, 283-324, 325-366, 367-409, 410-453
8
0.91
3FEX
C
P52292
Importin subunit alpha-1
Homo sapiens (Human)
152-193, 243-282, 283-324, 325-366, 367-409
5
0.91
5GXW
A
-
-
-
70-109, 152-193, 243-282, 283-324, 325-366, 367-409, 410-453
7
0.91
4E4V
B
P52292
Importin subunit alpha-1
Homo sapiens (Human)
68-109, 111-151, 152-193, 242-282, 283-324, 325-366, 367-408
7
0.91
4BA3
A
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
70-109, 152-193, 243-282, 283-324, 325-366, 367-409, 410-453
7
0.91
3HF1
B
Q7LG56
Ribonucleoside-diphosphate reductase subunit M2 B
Homo sapiens (Human)
104-146, 162-197, 198-244
3
0.91
4MZ6
E
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
72-109, 152-193, 242-282, 283-324, 325-366, 367-409, 410-454
7
0.90
1UPK
A
Q9Y376
Calcium-binding protein 39
Homo sapiens (Human)
64-111, 113-153, 154-195, 196-238
4
0.90
4EVA
C
Q02248
Catenin beta-1
Mus musculus (Mouse)
187-224, 225-267, 269-308, 309-351, 352-395, 396-431, 432-476, 477-520, 584-624
9
0.90
2Z6G
A
Q90424
Danio rerio (Zebrafish) (Brachydanio rerio)
150-180, 189-223, 224-266, 268-307, 308-350, 351-394, 395-430, 431-475, 476-521, 583-623, 624-665
11
0.90
4YI0
C
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
73-109, 112-151, 152-193, 242-282, 283-324, 325-366, 367-409, 410-454
8
0.90
4RV1
C
-
-
-
1-33, 34-75, 76-117, 118-159, 160-201, 202-243, 244-285, 286-327, 328-369, 370-411
10
0.90
4E4V
A
P52292
Importin subunit alpha-1
Homo sapiens (Human)
68-109, 111-151, 152-193, 243-282, 283-324, 325-366, 367-409, 410-454
8
0.90
4U5V
A
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
72-109, 152-193, 242-282, 283-324, 325-366, 367-409, 410-454
7
0.90
4RV1
D
-
-
-
1-33, 76-117, 118-159, 160-201, 202-243, 244-285, 286-327, 328-369, 370-411
9
0.90
4B8P
B
Q71VM4
Importin subunit alpha-1a
Oryza sativa subsp
107-147, 148-189, 232-273, 274-315, 325-358, 359-401, 402-450
7
0.90
3ZIO
A
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
72-109, 152-193, 243-282, 283-324, 325-366, 367-408, 410-454
7
0.90
5MFJ
A
-
-
-
85-126, 127-168, 169-210, 211-250
4
0.90
4R11
E
O44326
Beta-catenin-like protein hmp-2 {ECO:0000305}
Caenorhabditis elegans
155-194, 195-236, 237-280, 281-324, 325-361, 362-405, 407-449, 570-609
8
0.90
1WA5
B
Q02821
Importin subunit alpha
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
123-162, 163-204, 247-288, 289-330, 331-372, 373-415, 418-466
7
0.90
3ZIP
A
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
72-109, 152-193, 242-282, 283-324, 325-366, 367-408, 410-453
7
0.90
5MFL
C
-
-
-
43-84, 85-126, 127-168, 169-210, 211-252
5
0.90
3KND
A
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
70-109, 112-151, 152-193, 242-282, 283-324, 325-366, 367-409, 410-454
8
0.90
4RV1
A
-
-
-
1-33, 34-75, 76-117, 118-159, 160-201, 202-243, 244-285, 286-327, 328-369, 370-411
10
0.90
5KLT
B
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
72-105, 112-151, 152-193, 243-282, 283-324, 325-366, 367-409, 410-454
8
0.89
3L6Y
E
O60716
Catenin delta-1
Homo sapiens (Human)
359-397, 398-440, 441-482, 551-589, 648-689, 691-735
6
0.89
4EVA
A
Q02248
Catenin beta-1
Mus musculus (Mouse)
182-224, 225-267, 269-308, 309-351, 352-395, 396-431, 432-476, 477-520, 584-624, 625-662
10
0.89
3OUW
A
Q02248
Catenin beta-1
Mus musculus (Mouse)
182-224, 225-267, 268-308, 309-351, 352-396, 397-431, 432-476, 584-624, 625-664
9
0.89
3BTR
C
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
70-106, 152-193, 241-282, 283-324, 325-366, 367-409, 410-453
7
0.89
4RV1
B
-
-
-
2-33, 34-75, 76-117, 118-159, 160-201, 202-243, 244-285, 328-369, 370-411
9
0.89
3NMX
B
P25054
Adenomatous polyposis coli protein
Homo sapiens (Human)
471-511, 513-556, 557-599, 650-691, 692-733
5
0.89
4U5U
A
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
72-109, 152-193, 242-282, 283-321, 325-366, 367-409, 410-453
7
0.89
3IFQ
B
P14923
Junction plakoglobin
Homo sapiens (Human)
126-172, 173-215, 216-258, 260-299, 300-342, 343-385, 386-422, 423-467, 574-614, 615-653
10
0.89
3QHE
C
P25054
Adenomatous polyposis coli protein
Homo sapiens (Human)
513-556, 557-608, 609-649, 650-689
4
0.89
2GL7
A
P35222
Catenin beta-1
Homo sapiens (Human)
142-181, 182-224, 225-266, 269-308, 319-360, 392-431, 432-476, 477-520, 584-624, 625-663
10
0.89
1TH1
A
P35222
Catenin beta-1
Homo sapiens (Human)
145-181, 182-224, 225-267, 269-308, 309-351, 392-431, 477-520, 584-624, 625-664
9
0.89
4H3H
D
Q92797
Symplekin
Homo sapiens (Human)
30-71, 65-102, 103-146
3
0.89
3RZX
A
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
71-106, 152-193, 242-282, 283-324, 325-366, 367-409, 410-453
7
0.89
4YK6
A
P25054
Adenomatous polyposis coli protein
Homo sapiens (Human)
427-469, 470-512, 513-556, 557-608, 609-649, 650-691, 692-734
7
0.89
4PLQ
A
-
-
-
8-42, 43-84, 85-126, 127-168, 169-210, 211-252
6
0.89
3L6Y
A
O60716
Catenin delta-1
Homo sapiens (Human)
359-397, 398-440, 441-482, 551-590, 648-689, 691-735
6
0.89
5B56
B
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
71-109, 152-193, 243-282, 283-324, 325-366, 367-409, 410-453
7
0.89
1TH1
B
P35222
Catenin beta-1
Homo sapiens (Human)
146-182, 183-224, 225-266, 269-308, 309-351, 352-395, 396-431, 432-476, 489-520, 584-624, 625-664
11
0.89
3W3U
A
P32337
Importin subunit beta-3 {ECO:0000305}
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
91-132, 133-166, 167-207, 360-403, 404-441, 443-483, 851-892, 893-950
8
0.89
2YNR
A
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
72-106, 152-193, 242-282, 283-324, 325-366, 367-409, 410-453
7
0.89
4B18
A
P52294
Importin subunit alpha-5, N-terminally processed
Homo sapiens (Human)
79-116, 118-158, 159-200, 201-243, 244-285, 286-327, 328-369, 370-411, 413-460
9
0.89
3UVU
A
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
72-109, 152-193, 243-282, 283-324, 325-366, 367-409, 410-453
7
0.89
1G3J
A
P35222
Catenin beta-1
Homo sapiens (Human)
134-181, 182-224, 225-267, 269-308, 309-351, 352-395, 396-431, 432-476, 477-520, 584-624, 625-664
11
0.89
3L6Y
C
O60716
Catenin delta-1
Homo sapiens (Human)
359-397, 398-440, 441-482, 551-589, 648-689, 691-735
6
0.89
4UAF
B
P52293
Importin subunit alpha-1
Mus musculus (Mouse)
72-106, 152-193, 242-282, 283-324, 325-366, 367-409, 410-454
7
0.89