Database of Structural Repeats in Proteins

Ankyrin repeat - ANK


The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes. The few known examples from prokaryotes and viruses may be the result of horizontal gene transfers. The repeat has been found in proteins of diverse function such as transcriptional initiators, cell-cycle regulators, cytoskeletal, ion transporters and signal transducers. The ankyrin fold appears to be defined by its structure rather than its function since there is no specific sequence or structure which is universally recognised by it.

Link to other db

InterPro:

IPR002110

PROSITE:

PS50088

PRINTS:

PRO1415

SMART:

SM00248

Pfam:

PF00023

Number of PDB chains with ANK repeat: 640


1 - 50

PDB

Chain

UniProt

Name

Organism

Repeat annotation

Copies

Score

3TWQ
B
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
524-556, 557-589, 590-622
3
0.96
5ENT
E
-
-
-
13-45, 46-77, 78-110, 111-143
4
0.95
3Q9N
C
-
-
-
1-33, 34-65, 66-98, 99-131
4
0.95
3TWW
A
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
524-556, 557-589, 590-622
3
0.95
5BXO
A
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
525-557, 558-589, 590-622
3
0.95
3TWW
B
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
525-557, 558-589, 590-622
3
0.95
4Z68
A
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
525-557, 558-590, 591-622
3
0.95
3TWX
A
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
524-556, 557-589, 590-622
3
0.95
5BXU
A
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
524-556, 557-589, 590-622
3
0.95
3Q9U
D
-
-
-
1-33, 34-65, 66-98, 99-131
4
0.95
3TWS
A
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
524-556, 557-589, 590-622
3
0.95
3TWX
B
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
524-556, 557-589, 590-622
3
0.95
3TWS
B
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
524-556, 557-589, 590-622
3
0.95
3TWR
A
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
524-556, 557-589, 590-622
3
0.95
3TWV
D
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
524-556, 557-589, 590-622
3
0.95
5LW2
A
-
-
-
13-45, 46-77, 78-110, 111-143
4
0.94
5JHQ
C
O95271
Tankyrase-1
Homo sapiens (Human)
215-247, 248-279, 280-312, 368-400, 401-432, 433-465, 556-588, 589-621
8
0.94
5AAO
C
-
-
-
13-45, 46-77, 78-110, 111-143
4
0.94
5GIK
A
-
-
-
13-45, 46-77, 78-110, 111-143
4
0.94
3UTM
A
Q6PFX9
Tankyrase-1
Mus musculus (Mouse)
361-393, 394-426, 427-458, 549-581, 582-614
5
0.94
1UOH
A
O75832
26S proteasome non-ATPase regulatory subunit 10
Homo sapiens (Human)
5-37, 39-71, 72-103, 104-136, 137-169, 170-202
6
0.94
3C5R
B
Q99728
BRCA1-associated RING domain protein 1
Homo sapiens (Human)
427-459, 460-491, 492-524
3
0.94
4CZ2
D
Q96NW4
Ankyrin repeat domain-containing protein 27
Homo sapiens (Human)
462-494, 495-527, 528-559, 563-595
4
0.94
4U8V
D
-
-
-
13-45, 46-78, 79-111, 112-143
4
0.94
4DX7
D
-
-
-
13-45, 46-77, 78-110, 111-143
4
0.94
1QYM
A
O75832
26S proteasome non-ATPase regulatory subunit 10
Homo sapiens (Human)
5-37, 39-71, 72-103, 104-136, 137-169, 170-202
6
0.94
5AAO
J
-
-
-
12-45, 46-77, 78-110, 111-143
4
0.94
4U96
D
-
-
-
13-45, 46-77, 78-110, 111-143
4
0.94
5JHQ
D
O95271
Tankyrase-1
Homo sapiens (Human)
215-247, 248-279, 280-312, 367-399, 400-432, 433-465, 555-587, 589-621
8
0.94
3Q9N
D
-
-
-
2-33, 34-65, 66-98, 99-131
4
0.94
4HLL
A
-
-
-
13-45, 46-78, 79-110, 111-143
4
0.94
4ATZ
D
-
-
-
13-45, 46-77, 78-110, 111-143
4
0.94
5AAO
D
-
-
-
13-45, 46-77, 78-110, 111-143
4
0.94
5ENS
D
-
-
-
13-45, 46-78, 79-110, 111-143
4
0.94
3NOC
D
-
-
-
13-45, 46-78, 79-110, 111-143
4
0.94
5NC5
D
-
-
-
13-45, 46-78, 79-110, 111-143
4
0.94
2P2C
Q
-
-
-
13-45, 46-78, 79-110, 111-143
4
0.94
4DX5
D
-
-
-
13-45, 46-78, 79-110, 111-143
4
0.94
4ATZ
E
-
-
-
13-45, 46-78, 79-110, 111-143
4
0.94
5AAO
E
-
-
-
12-45, 46-77, 78-110, 111-143
4
0.94
3EHR
B
Q92882
Osteoclast-stimulating factor 1
Homo sapiens (Human)
74-104, 105-137, 138-170
3
0.94
5EN5
E
-
-
-
13-45, 46-78, 79-110, 111-143
4
0.94
5ENS
E
-
-
-
13-45, 46-78, 79-110, 111-143
4
0.94
4CZ2
F
Q96NW4
Ankyrin repeat domain-containing protein 27
Homo sapiens (Human)
462-494, 495-527, 528-559, 563-595
4
0.94
4U8Y
D
-
-
-
13-45, 46-77, 78-110, 111-143
4
0.94
2XZT
G
-
-
-
13-45, 46-78, 79-110
3
0.94
2P2C
R
-
-
-
13-45, 46-78, 79-110, 111-143
4
0.94
3TWQ
A
Q9H2K2
Tankyrase-2
Homo sapiens (Human)
491-523, 525-557, 558-589, 590-622
4
0.94
4LSZ
E
-
-
-
13-45, 46-77, 78-110, 111-143
4
0.94
5JMN
E
-
-
-
13-45, 46-77, 78-110, 111-143
4
0.94